The Institute for Research in Biomedicine (IRB), founded in 2000 in Bellinzona, has been affiliated to USI in 2010. Financed by private and public institutions, and by competitive grants, the IRB currently hosts nine research groups and employs around 100 researchers from all over the world. Research focuses on the human host defence against infections, tumours and degenerative diseases. With more than 440 publications in leading scientific journals, the IRB has gained an international reputation as a centre of excellence in immunology and cell biology. The IRB is also a post-graduate educational centre: so far 62 IRB students have completed their PhD thesis.