Mariagrazia Uguccioni received a degree in Medicine from the University of Bologna (IT) where she specialized in Haematology in 1994. From 1993 to 2000 she was a member of the Theodor Kocher Institute, University of Bern (CH), and since 2000 she is group leader at the IRB, and vice-director since 2010. In 2016 she has been nominated extraordinary Professor at the Medical faculty of Humanitas University (Milan, IT). She was elected Member of the Bologna Academy of Science in 2009 for her studies on the relevance of chemokines in human pathology. Mariagrazia Uguccioni’s research covers various aspects of human haematology and immunology: chemokine expression and activities in normal and pathological conditions, leukocyte activation and traffic, natural chemokine antagonists and synergy-inducing chemokines. Her group continue focusing on chemokine activities in human inflammatory diseases, tumours, and infections, and is recently dissecting the mechanisms leading to chemokine synergism in leukocytes, and the modifications occurring in leukocytes from patients with chronic inflammatory conditions, which lead to dysfunction of the chemokine receptors.