Rectal prolapse in laboratory-housed macaques
prevalence, risk factors, and enhanced treatment modality
Additional information
Authors
Leleu J.,
Simon M.,
Cavalcanti Pereira da Silva L. C.,
Virgilio T.,
De la Garza M. A.,
Bakker J.
Type
Journal Article
Year
2024
Language
English
Abstract
Rectal prolapse is a common condition in laboratory-housed macaques, usually associated with recurrent gastroenteritis and stress. However, evidence for both statements is lacking. Therefore, the prevalence of rectal prolapses and their risk factors in laboratory-housed macaques have yet to be assessed. In addition, a standard of care pharmacological treatment remains to be recognized and documented. Thus, a retrospective study involving 816 laboratory-housed macaques was conducted, in which the prevalence, risk factors, and treatment success of rectal prolapses was assessed. The prevalence was shown to be 3.92%, and all cases could be either directly or indirectly linked to stress factors. By eliminating the suggested stressor, most rectal prolapses reverted naturally (69%). Moreover, we discuss the advantage of the ancillary administration of hyoscine butylbromide and metamizole as a treatment modality.
Keywords
Rectal prolapse, Macaques, Treatment, Manual reposition, Metamizole, Hyoscine butylbromide, Prevalence, Stress, Etiology, Risk factor
Journal
Laboratories
Volume
1
Number ( Month )
3
Pages (or article number)
148-157
Diffusion
License
CC BY
Visibility
Public
Status open access
Gold
