Faculty of Biomedical Sciences
Funded projects
Approved (4)
- Cejka P. (2027) The role of BRCA1 and BRCA2 protein complexes in the maintenance of genome stability
- Monticelli S. (2026) Post-transcriptional regulation of T lymphocyte responses by RNA-binding proteins
- Uguccioni M., Cecchinato V., Martini V. (2026) 3rd INTERNATIONAL WORKSHOP ON ANKYLOSING SPONDYLITIS: TALES OF MOLECULES AND PATIENTS
- Albanese E. (2026) Education, work and Cognitive Stimulation across the Life-course: Evidence from Natural Policy Experiments
In progress (59)
- (2026) Harnessing Gamma-Delta T Cells for Cancer Therapy
- Fadda M. (2026) E-QUAL - Advancing Open Science and Open Research Data practices for qualitative research at USI (E-QUAL)
- Moretti M., Arrigoni C. (2026) SSB+RM conference Lugano 2026
- Ravenda F. (2026) USI Doctoral Mobility - Federico Ravenda
- Fadda M. (2026) E-QUAL - Advancing Open Science and Open Research Data practices for qualitative research at USI
- Cavalli A. (2026) Therapeutic Strategies to Stabilize and Activate PTEN in Cancers and Rare Disorders with Monoallelic PTEN Loss
- Alimonti A. (2026) Targeting UPR Stress Signaling Pathways in PMN-MDSC to Overcome Therapy Resistance in Prostate Cancer
- Castelnovo A. (2026) Mental and Neural Correlates of NREM Parasomnias in Children
- Cavalli A. (2026) Development of an AI-driven platform for the discovery of conserved conformational epitopes (CoCoTopes) and their use in antibody discovery and vaccination
- Bertoni F. (2026) Wiskott-Aldrich Syndrome Protein in Lymphomagenesis: Unraveling the Interplay Between Somatic Mutations, B-cell Receptor Signaling and Actin Dynamics
- Nobs S. P. (2025) Discovering the Diversity and its Drivers of Novel Lung Dendritic Cell Subsets in Asthma
- Iezzi G. (2025) Fusobacterium nucleatum as surrogate target for colorectal cancer immunotherapy
- Cejka P. (2025) Mechanism of DNA double-strand break repair and its regulation
- Calcinotto A. (2025) Development and Optimization of P48: A Microbial-Inspired Therapeutic for Prostate and Ovarian Cancer
- Cascione L. (2025) Molecular and Cellular Characterization of MALT Lymphoma Across Anatomical Sites: Integrative Transcriptomic and Epigenetic Approaches
- Bersini S., Baggiolini A. (2025) Enhancing human brain organoid complexity through biofabrication of a perfusable vasculature
- (2025) The Roles and Regulation of Protein Phase Separation in Immune Responses and Aging
- Cejka P. (2025) Extranuclear activities of genome maintenance protein complexes in stress response
- Valgimigli M. (2025) TicIn for the Treatment of coronAry lesioNs – PlAque Regression AnD stabilISation with drug Eluting balloons (TITAN-PARADISE)
- Geiger R. (2025) Programmable and dynamically-responsive bacterial therapeutics for cancer immunotherapy
- González F. S. (2025) T-RAFIC - Training network for tracking and controlling therapeutic immune cells in cancer
- Theurillat J. P. (2025) ERF-202: A Hidden Tumor Suppressor Isoform Linked to Prostate Cancer Progression
- Nobs S. P. (2025) Unraveling the intersection between nutrition and lung viral infection
- Robbiani D. (2025) Human antibodies to flavivirus threats
- Camerini A. L. (2025) AWARE: Mental Health Portrayals on Social Media and Implications on Adolescents’ Awareness and Well-being
- Barile L. (2025) Targeting an Antisense lncRNA of the Desmoplakin Gene for Treating Arrhythmogenic Cardiomyopathy in Human Cellular Model
- Bersini S. (2025) A high-throughput microphysiological platform to analyze the role of the aging human vasculature in melanoma metastases
- Fiordelli M. (2025) CoPeC - Building Care Pathways for Dementia: An integrated and participatory approach to preserving autonomy
- Nobs S. P. (2024) Unraveling host-microbiome interactions in lung fibrosis
- Limongelli V. (2024) Learning the activation mechanism in G protein coupled receptors from free energy calculations
- Cavalli A., Robbiani D. (2024) AntibodyGPT: Language Modeling for fast ex novo Monoclonal Antibody Generation and Evolution
- Valgimigli M. (2024) Cerebral LEsion by mAgnetic Resonance in the MATRIX-2 (CLEAR-MATRIX-2)
- Rossi D. (2024) Oncogenic perturbations of the non-coding regulatory genome in classic Hodgkin lymphoma
- Moretti M. (2024) Investigating the role of senescence in the development of incurable prostate cancer bone metastases within a human 3D in vitro model of aging bone
- Monticelli S. (2024) Bridging T Cell Receptor and Integrin Signaling Pathways with SKAP2 - Functional Insights and Biochemical Characterization
- Molinari M. (2024) ER-phagy: the lysosomal control of endoplasmic reticulum homeostasis
- Carbone G. (2024) EHF/ESE3 transcription factor as a regulator of prostate epithelial cell differentiation and stem cell properties
- Cecchinato V. (2024) NATURAL AUTOANTIBODIES TARGETING CHEMOKINES IN HIV-1 INFECTION AND PATHOGENESIS
- Galati S. (2024) Disabling levodopa-induced dyskinesia in Parkinson’s disease: the role of sleep
- Camerini A. L. (2024) The role of offline, hybrid, and online play in socio-emotional and cognitive functioning among school-aged children and adolescents in Italian-speaking Switzerland: A mixed-methods study
- Zucca E. (2024) Multilayer taxonomy of nodal marginal zone lymphoma
- Calcinotto A. (2024) Exploiting neutrophil heterogeneity as mediator of synthetic lethality in breast cancer
- Calcinotto A. (2024) Dissecting the role of intracellular bacteria and neutrophil heterogeneity in cancer susceptibility and progression
- Geiger R. (2024) IMMERGE - Storming Immune Monogenic Conditions through Multiomic and Gene Editing Approaches
- Alimonti A. (2024) Development of a drug discovery platform to identify microbiome-derived therapeutics
- Geiger R. (2023) TOP-GUT - Training for Organoids modelling Physiology and Pathology in the human gastrointestinal tract
- Bano B. (2023) Fill the implementation gap: a mixed methods study of theory-based adaptation and implementation approaches and processes of a low-dose psychosocial intervention for caregivers
- Alimonti A. (2023) Microbiota regulation of prostate cancer growth and metastatic dissemination
- Molinari M. (2023) Protein quality control and degradation from the endoplasmic reticulum
- Varani L. (2023) Multispecific antibodies against infectious diseases
- Bersini S. (2023) I’M AGEING - Integrated Microphysiological-omic approach to identify blood proteins reverting vascular AGEING
- Baggiolini A. (2023) Oncogenic Competence at the Cellular and Multicellular Level in Melanoma
- Baggiolini A. (2023) Human pluripotent stem cell-derived model of perineural tumor microenvironment
- Raballo A. (2022) FAMILY - Running in the FAMILY - Understanding and predicting the intergenerational transmission of mental illness
- Cejka P. (2022) Regulation of the MutL-gamma (MLH1-MLH3) nuclease in DNA mismatch repair and meiosis
- González F. S. (2022) C-type lectin receptors and their implication in the innate response against respiratory pathogens
- Sabbioni G. (2022) PARC - PARTNERSHIP FOR THE ASSESSMENT OF RISKS FROM CHEMICALS
- Cejka P. (2022) BRCA INSIGHTS - Understanding the functions of the BRCA protein complexes in DNA break repair and in replication stress
- Limongelli V. (2021) CoMMBi - Computational Microscope on Molecular Binding: from atom to cell membrane scale
Completed (275)
- Castelnovo A. (2026) From Sleep Slow Waves to Sleepwalking: Markers of Arousal Dysregulation in NREM Parasomnias
- Fadda M. (2025) Advanced Care Planning
- Manconi M. (2025) WORLD SLEEP FORUM 2025 FORENSIC SLEEP MEDICINE
- Amati R. (2025) Swiss Public Health Conference 2025 - Mental Health and Wellbeing: Investing in Mental Wealth
- Gasparri M. L. (2025) Patients with breast cancer and nodal metastasis: Sentinel lymph node biopsy versus Targeted Axillary Dissection after primary systemic treatment. A Randomized Controlled trial
- Manconi M. (2025) Assessing heart rate variability and pupil dynamics in patients with NREM sleep parasomnias
- Limongelli V. (2025) FMdb - FMdb: the database to perform funnel-metadynamics calculations on GPCR systems
- Junqueira C. (2024) Expanding our immununological detection power with FACSDiscover S8 sorter
- Albanese E. (2024) GMH - Global Mental Health workshop
- Limongelli V. (2024) Understanding the function of G-Protein Coupled Receptors by atomistic and multiscale studies
- Valgimigli M. (2024) TicIn for the Treatment of coronAry lesioNs – PlAque Regression AnD stabilIsation with Sirolimus Elution (TITAN-PARADISE)
- Theurillat J. P. (2024) Translational Prostate Cancer Symposium: Horizons in Prostate Cancer Research
- Geiger R. (2024) CRISPR screens in human tumor model to identify factors regulating the antitumor activity of dendritic cells
- Theurillat J. P. (2024) Mining and Predicting Prostate Cancer Progression for Better Patient Care
- Theurillat J. P. (2024) PCaMiner - Prototyping the harmonization and the integrated mining of prostate cancer RNA se-quencing data sets
- Mangani D. (2024) Modulation of P2X receptor signaling in intestinal microbiota/host cross talk to improve the efficacy of immunotherapy in solid tumors.
- Fadda M., Göggel Simonetti B., Camerini A. L. (2024) STRONGHEAD - Young athletes and concussion: a pilot study of the situation in Italian-speaking Switzerland
- Manconi M. (2023) PTPRD fluctuation in pregnancy with and without Restless Legs Syndrome
- Cassotta A. (2023) Dynamics of immune response after myocardial infarction
- Virgilio T. (2023) Reprogramming Metastasis Infiltrating NK (MINKs) into tumor killers
- Sgrignani J. (2023) Restoring PTEN function by small molecule induced deubiquitination
- Guarda G. (2023) Dimension++ - Conformational changes in NLRC5 function
- Albanese E., Amati R., Fiordelli M. (2023) IN-PHASE - Inter-university pre-grad Public Health Master for the SSPH+
- Camerini A. L., Fadda M. (2023) Prevention and management of sport-related traumatic brain injury among children and youth
- Fiordelli M. (2023) Free from fear. Reframing Dementia through the Eyes of Caregivers.
- Uguccioni M. (2023) 2ND INTERNATIONAL WORKSHOP ON ANKYLOSING SPONDYLITIS: TALES OF MOLECULES AND PATIENTS
- Varani L. (2023) Immunotherapy for Infectious disease (ITID) conference 2023
- Alimonti A. (2023) New frontiers in biological and environmental determinants of aging
- Robbiani D. (2023) The human immune response to West Nile virus infection
- Rossi D., Zucca E. (2023) The Lugano classification for staging and response assessment of lymphoma: Looking towards the future
- Galati S. (2023) 2023 Annual Meeting of the SSN
- González F. S., Krause R., Pizzagalli D. U. (2023) RE2Vital - REuse and REproducibility of intraVITAL microscopy via open data practices in image-driven immunological research
- Carbone G. (2023) Novel epigenetic players in castration-resistant prostate cancer: functional and therapeutic impact
- (2023) ModelArchive - Open Research Data (ORD) best practices for computational macromolecular models
- Geiger R., Catapano C., Cejka P., Sallusto F., Theurillat J. P. (2022) timsTOF Pro 2 for clinical proteomics
- Rossi D. (2022) Uncovering the pathophysiology and vulnerability of minimal residual disease persisting under venetoclax in patients with chronic lymphocytic leukemia
- Alimonti A. (2022) Development of a senolytic of natural origin for antiaging therapy
- Limongelli V. (2022) Understanding function of G-Protein Coupled Receptors by atomistic and multiscale simulation
- Bertoni F. (2022) Protein-coupled receptors of the olfactory receptors’ family provide novel therapeutic opportunities against lymphoma cells
- De Gottardi A. (2022) Quality of life of patients living with vascular LIVEr diseaseS. Developing research on the social impact of rare diseases
- Theurillat J. P. (2022) Transcriptome-Guided Reverse Engineering of Human Prostate Cancer
- Varani L. (2022) SARS-CoV-2: understanding the entry, multi-organ spread, and immune response in the context of vaccination and re-infection
- Catapano C. (2022) Liver-specific inhibition of Lin28B for treatment of hepatocarcinoma
- Alimonti A. (2022) Optimisation of therapies targeting the gut microbiota in prostate cancer
- Geiger R. (2022) A human tumor model for preclinical immunotherapy trials
- Thelen M. (2022) 2022 Gordon Research Conference on: Chemotactic Cytokines
- Perale G. (2022) SpinoSave - Clinically relevant hydrogel for an integrative approach of stem cell therapy in spinal cord injury patients
- Pavon A. G. (2022) The role of cardiovascular magnetic resonance in non-ST-elevation-myocardial infarction
- Barile L. (2022) Extracellular Vesicles as next-generation clinical biomarkers and therapeutic agents FET-PROACT project MARVEL workshop
- Monticelli S. (2022) Excellence Grant - Cell-intrinsic mechanisms modulating inflammatory responses in T lymphocytes
- Varani L. (2022) ISIDORe - Integrated Services for Infectious Disease Outbreak Research
- Rossi D. (2022) Understanding how clonal hematopoiesis feeds lymphoma
- Cavalli A. (2022) KIAA1199 and hyaluronic acid signaling: a promising therapeutic approach for glomerular disease.
- Cavalli A., Robbiani D. (2022) Rational design of neutralising antibodies resilient to virus escape
- Alimonti A., Barile L., Cippà P. (2021) Targeting cellular senescence in physiological, pathological and iatrogenic conditions
- Cejka P. (2021) First steps in DNA double-strand break repair: underlying mechanisms and regulation
- Alimonti A. (2021) Excellence Grant –Development of senolytic therapies for chemotherapy-treated prostate cancer
- (2021) Improving Current Standards for Event Prediction After Myocardial Infarction Through Artificial Intelligence
- De Gottardi A. (2021) Mechanisms of Paneth cell's driven mediators in the development of advanced chronic liver disease
- Suggs L. S., Fadda M. (2021) PERSPECTIVES - Understanding perspectives about COVID-19 vaccine and vaccination among school staff in Switzerland. A mixed-methods study
- Miano S. (2021) Clinical and genetic characteristic of narcolepsy typed I patients with HLA negative
- Fiordelli M. (2021) Critical health literacy in secondary schools: a pilot study in Ticino
- Bertoni F. (2021) Evaluation of non-ATP competitive PI3K# inhibition with IOA-244 in the treatment of lymphoma
- Camerini A. L. (2021) Siete connessi? Verso un uso consapevole dello smartphone tra i bambini e adolescenti
- Albanese E. (2021) RISE - Raising awareness for mental health in people affected by neuropediatricdiagnosis leading to severe disability
- Robbiani D. (2021) Human antibodies to tick-borne flaviviruses
- Guarda G. (2021) Deciphering Mycregulation and funcion in NK cells
- De Gottardi A., Krause R., Pizzagalli D. U. (2021) Predicting hospital admission in patients with advanced chronic liver disease (ACLD): a pilot study with a trajectomics approach
- González F. S., Virgilio T. (2021) Characterizazion of the Innate Immune Responses against SARS-CoV-2
- Guarda G. (2021) Understanding the connections between cellular metabolism, MHC class I regulation, and the immune response
- González F. S. (2021) Le molte facce del contagio
- Mira A., Auricchio A. (2021) Multivariate spatio-temporal models with latent dynamics for cardiovascular disease prediction with heterogeneous factors
- Robbiani D. (2021) Sources of genomic instability in B cell malignancy
- Geiger R. (2021) CRISPR activation and knockout screens to augment anti-tumor T cell responses
- Fadda M. (2021) Between autonomy and public good: Exploring individuals’ understanding of the ethical implications of COVID-19 public health response measures
- Meneguzzo M. (2021) SLHS2 - Swiss Learning Health System 2
- Molinari M. (2021) Non-competitive pharmacologic chaperones developed through the Site-directed Enzyme Enhancement Therapy (SEE-Tx) technology for the treatment of rare genetic and neurodegenerative diseases
- Bertoni F. (2020) Enhancer RNAs in B cell lymphomas
- Alimonti A. (2020) Development of a senolytic of natural origin for anti-aging therapy
- Bertoni F. (2020) Anti-L1CAM antibody therapy for rare diseases
- Grassi F. (2020) Investigating the enhanced mucosal immune response against vaccines and protection against bacterial infections promoted by the ATPase Apyrase
- Theurillat J. P. (2020) Deciphering the Biology and the Therapeutic Implications of SPOP Mutant Prostate Cancer
- Bertoni F. (2020) Development of a microfluidic platform for real-time detection of SARS-CoV-2 virus based on multifunctional silica membrane biosensors
- Uguccioni M. (2020) Development of an innovative therapy for ANCA- associated vasculitis (AAV)
- Albanese E. (2020) GlobalP3HS- GLOBALJIANG - SSPH+ Global PhD Program in Public Health Sciences
- Limongelli V. (2020) REDAC - REpositioning Drugs Against COVID-19
- Rossi D. (2020) Discovery of genetic/epigenetic addictions in NOTCH2/KLF2-mutated lymphoma
- Albanese E. (2020) CORONAIMMU - SSPH+ Corona Immunitas
- Monticelli S. (2020) RNA-binding proteins and control of mRNA metabolism in the regulation of adaptive immunity in humans
- Grassi F. (2020) Structure and function of secretory IgA repertoire in intestinal homeostasis
- Varani L., Robbiani D. (2020) ATAC - Antibody therapy against coronavirus (COVID-19)
- Napoli S., Bertoni F. (2020) Characterization of specific enhancer RNAs involved in ibrutinib resistance mechanism in marginal zone lymphoma
- Albanese E., Fiordelli M. (2020) iSupport - Local adaptation of the WHO interventions for informal caregivers of people with dementia
- Grassi F. (2020) Intestinal ecosystem conditioning to improve the outcome of cancer immunotherapy with checkpoint inhibitors
- Fadda M. (2020) Advanced issues in qualitative research in healthcare
- Albanese E., Morese R. (2020) M-health - Social Media Mental Health Surveillance M-HEALTH: Detecting suicide Ideation in Switzerland using Twitter data
- Sallusto F. (2020) New approaches to study T cell activation, differentiation and plasticity in humans
- Catapano C. (2020) Nanoparticle-based delivery and combinatorial therapies for cancer
- Albanese E. (2020) Pop-health - New technologies to improve mental health of the population
- Sabbioni G. (2020) HBM4EU - European Human Biomonitoring Initiative
- González F. S., Krause R. (2019) IMMUNEMAP - Enabling data-driven immunological research by making two-photon intravital microscopy data FAIR
- Alimonti A., Calcinotto A., Catapano C., Iezzi G., Rossi D. (2019) High parameter cell analysis by BD FACSymphony
- Gaudio E., Spriano F. (2019) A novel combined approach of nuclear magnetic resonance (NMR) and Mass spectrometry to isolate the protein targets of chemical small molecules.
- Iezzi G. (2019) Immunomodulatory effects played by gut microbiota associated with T cell infiltration and favorable prognosis in human colorectal cancer
- Fiordelli M., Albanese E. (2019) 100%SwissDem
- Albanese E. (2019) SwissDEM - Dementia burden, trends, and risk factors in three Swiss cantons
- Carbone G. (2019) The ETS transcription factor ESE3/EHF as a regulator of prostate epithelial cell differentiation and stem cell properties
- Molinari M. (2019) CHAPERONE - Allosteric chaperones to treat rare lysosomal storage disorders
- Theurillat J. P. (2019) Deciphering and Targeting the Cancer Ubiquitylome
- Barile L. (2019) Technical challenges of extracellular vesicle research
- Albanese E. (2019) SwissDem - SwissDEM "Community engagement project"
- Molinari M. (2019) Protein folding, quality control and degradation in the endoplasmic reticulum
- Rossi D. (2019) Bridging liquid biopsy into management of lymphoma patients: development of frameworks for clinical research and recommendations for clinical practice
- Guarda G. (2019) Deciphering the divergent roles of phosphatases in PD-1 and cytokine signaling
- Varani L. (2019) Characterization of antibody-antigen interactions in human pathogens
- Geiger R. (2019) The development of a platform to rapidly identify tumor antigene-specific T cells receptors for therapy
- Moretti M. (2019) Ewing Sarcoma metastatic invasion dissected through new 3D vascularized human microfluidic models recapitulating endochondral ossification
- Barile L. (2019) EXaCT - EXosomes based Combination Therapy to target multiple signaling within cardioprotective pathways
- Sallusto F. (2019) Lymphocyte T helper (Th) cell differentiation in patients with inborn errors of immunity to Mycobacterium and/or Candida species
- Geiger R. (2019) TIL-FIT - Increasing the fitness of tumor-infiltrating T cells for cellular immunotherapy
- Conte G. (2018) A Novel Approach to Assess Atrial Electrical Abnormalities in Patients with Brugada Syndrome: From the ECG to the Creation of a Patient-Specific Cardiac Model
- Thelen M. (2018) Function of ACKR3 in immune cell trafficking in lymphoid organs
- Albanese E. (2018) Pilot and Validation Study for the Ten Sixty Swiss Study
- Albanese E. (2018) Impact of Alzheimer's disease and other forms of cognitive impairment in Ticino
- Alimonti A. (2018) Development of senolytic therapies for chemotherapy-treated prostate cancer
- Theurillat J. P. (2018) Understanding Synthetic Sick Interactions of Prostate Cancer Driver Genes
- (2018) Infra-slow oscillations during sleep
- Rossi D. (2018) CLLCLONE - Harnessing clonal evolution in chronic lymphocytic leukemia
- Monticelli S. (2018) NCCR RNA& Disease - NCCR RNA & Disease ( subproject The role of RNA in disease mechanisms)
- Zucca E. (2018) IELSG46 - Integrated Molecular and Clinical Profiling to Optimize Outcome Prediction in Splenic Marginal Zone Lymphoma
- Albanese E. (2018) STRiDE - Dementia prevalence, costs and impact in seven developing countries: A STRiDE project
- Monticelli S. (2018) Transcriptional control of human T lymphocyte pathogenic potential in autoimmunity
- Camerini A. L. (2018) MEDIATICINO 2.0 - Blessing or Curse? Smartphones in the Life of Adolescents
- Theurillat J. P. (2017) Development of predictive pre-clinical cell culture models for prostate cancer
- González F. S. (2017) TANTUMorNEUVACCINE - Neutrophil subtypes: distinct cellular targets for therapeutic intervention
- Cejka P. (2017) Beyond DNA end resection: Role of homologous recombination in the maintenance of genome stability
- Lanzavecchia A. (2017) Antibody diversification by templated insertions: impact, mechanism and exploitation
- González F. S. (2017) Role of lymph node phagocytes in the regulation of the IgG-mediated suppression of the immune response to influenza vaccine
- Sallusto F. (2017) RT Cure - Rheuma Tolerance for Cure
- Uguccioni M. (2017) International Meeting “Ankylosing Spondylitis: Tales of Molecules and Patients”
- Catapano C. (2017) Targeting metabolic reprogramming and plasticity of cancer stem cells to impact on tumor progression and treatment resistance
- Catapano C. (2017) Epigenetic cross-talks and novel therapeutic strategies to prevent disease progression in ERG fusion positive prostate cancer
- Rossi D. (2017) Molecular prediction of long term benefit from ibrutinib in high risk chronic lymphocytic leukemia
- Grassi F. (2017) Role of ATP gated ionotropic P2X7 receptor in regulating adaptive mucosal immunity, host-microbiota mutualism
- Albanese E., Crivelli L., Traber R. (2017) Foresight - “There's no place like home”: Testing the cost-effectiveness of home treatment for acute mental illness in Ticino
- Sallusto F. (2016) ZIKAlliance - A global alliance for Zika virus control and prevention
- Cejka P. (2016) HRMECH - Nucleases in homologous recombination: from basic principles to genome editing
- Sallusto F. (2016) Studies on T cell activation, differentiation and plasticity in humans
- Carbone G. (2016) The ETS transcription factor ESE3/EHF as a regulator of prostate epithelial cell differentiation and stem cell properties
- Limongelli V. (2016) Extensive computer simulations investigate TPP1-TERT protein-protein interaction
- Cavalli A. (2016) Identification of structural determinants of light chain amyloidosis
- Guarda G. (2016) T CELL-INTRINSIC ROLE OF PATTERN RECOGNITION RECEPTORS
- Alimonti A. (2016) Immune-senescence - Dual targeting of senescence and tumor immunity for cancer therapy
- Montagner S. (2016) Epigenetic regulation of mast cell differentiation and function
- Auricchio A. (2016) Novel electro-mechanical phenotyping of heart failure patients candidate for cardiac resynchronization therapy
- Paganetti P. (2016) Mechanisms of tau proteotoxicity in neurodegeneration
- Varani L. (2016) Characterization of antibody-antigen interactions in human pathogens
- Limongelli V. (2016) MuTaLig - Multi-target paradigm for innovative ligand identification in the drug discovery process
- Bertoni F., Zucca E. (2016) Targeted agents in splenic marginal zone lymphoma: mechanisms of resistance and new combinations
- Lanzavecchia A. (2016) EHVA - European HIV Vaccine Alliance (EHVA): a EU platform for the discovery andevaluation of novel prophylactic and therapeutic vaccine candidates
- Molinari M. (2016) Protein folding, quality control and degradation in the endoplasmic reticulum
- Thelen M. (2015) Interplay of classical and atypical chemokine receptors in immune cell trafficking and dynamic microarchitecture of the secondary lymphoid organs
- Manconi M. (2015) Perinatal depression: chronobiology, sleep related risk factor and light therapy
- Manconi M. (2015) RLS/PLMS - Infra-slow oscillations during sleep, after acute sleep deprivation, and in patients with restless legs syndrome/periodic leg movements during sleep
- Lanzavecchia A. (2015) BROADimmune - Structural, genetic and functional analyses of broadly neutralizing antibodies against human
- Cejka P. (2015) Repair of damaged DNA by homologous recombination and related pathways
- Thelen M. (2015) The Atypical Chemokine Receptor ACKR3: Function in vivo in Immune Responses and Coupling to Signal Transduction Pathways
- Varani L., Catapano C., Cavalli A., Lanzavecchia A., Thelen M., Uguccioni M. (2015) Acquisition of a 600MHz solution NMR spectrometer
- Lanzavecchia A. (2015) Analytic vaccinology
- Thelen M. (2015) First European Chemokine and Cell Migration Conference (ECMC2015)
- Grassi F. (2015) Systemic impact of purinergic P2X7 receptor activity at the interface between gut-associated lymphoid tissue and commensal microflora
- Monticelli S. (2015) DNA methylation landscape in mast cell differentiation and systemic mastocytosis
- Molinari M. (2014) ER-phagy mechanisms to maintain and restore endoplasmic reticulum homeostasis
- Sallusto F. (2014) UnmetMS - Unraveling the immune etiology of multiple sclerosis
- Theurillat J. P. (2014) Genetically-Induced Aberrant Chromatin States in Prostate Cancer – Biology and Therapy
- Catapano C., Carbone G. (2014) Promoter-proximal long non-coding RNAs and epigenetic regulatory networks in prostate cancer
- González F. S. (2014) A massively parallel space-time connected approach based on implicit active contour methods to track leukocytes observed by multiphoton intra vital and confocal microscopy
- González F. S. (2014) IMPORED - Intravital imaging of polymicrobial respiratory diseases
- Bertoni F. (2014) Functional analysis of altered transcriptional pathways in diffuse large B-cell lymphoma of the ABC subtype
- Grassi F. (2013) System for on-line Monitoring of Human Metabolic Conditions in Critical patients
- Varani L. (2013) Mass Virus Typer: New Technology for Direct Virus Characterization
- Sallusto F. (2013) Studies on T cell activation, differentiation and plasticity in humans
- Kwee I., Bertoni F. (2013) Steiner Trees for Functional Analysis in Cancer System Biology
- Monticelli S. (2013) Role of microRNAs in reactivation of encephalitogenic T cells
- Lanzavecchia A. (2013) Tuning of immune homeostasis and immune response by persistent viral infections
- González F. S. (2013) IRINVAC - Immune responses to influenza vaccine
- Grassi F. (2013) Innovative Enabling Micro-Nano-Bio-technologies for Implantable systems in molecular medicine and personalized therapy – Project prolongation
- Sallusto F. (2013) PREDICT - Dissecting the human T cell response to pathogens, allergens, and self-antigens
- Manconi M., Auricchio A. (2013) Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome - the AUTO-REST Study
- Carbone G. (2013) The ETS transcription factor ESE3/EHF as a regulator of prostate epithelial cell differentiation and stem cell properties
- Zucca E. (2013) IELSG37 - A randomized, open-label, multicentre, two-arm phase III comparative study assessing the role of involved mediastinal radiotherapy after Rituximab containing chemotherapy regimens to patients with newly diagnosed Primary Mediastinal Large B-Cell
- Uguccioni M. (2013) Impact of Synergy-inducing Molecules on Chemokine Activities
- González F. S., Sallusto F., Thelen M. (2012) Acquisition of a 2-Photon microscope for intravital analysis
- Grassi F. (2012) TIROTAPS - Transient Receptor Potential Melastatin-like 7 (TRPM7) in Regualation of T cell subsets and Purinering Signaling
- Lanzavecchia A. (2012) Human B cells and plasma cells in health and diseases
- Thelen M. (2012) Conventional and atypical chemokine receptors: different mechanisms of function and common responses
- Lanzavecchia A. (2012) LINFOEPAB - CD4 T and B Lymphocytes in hepatitis B patients: role in acute and chronic infection
- Varani L. (2012) Antibody-antigen interactions in Dengue virus
- Grassi F. (2012) Purinergic control of adaptive immunity by P2X7 receptor
- Molinari M. (2012) Protein folding, quality control and degradation in the endoplasmic reticulum
- Lanzavecchia A. (2012) ABIRISK - Anti-Biopharma ceutical Immunization: Prediction and anlysis of clinical rlevance to minimize the risk
- Monticelli S. (2012) Analysis of novel molecular networks underlying mast cell development, function and disease: specific roles of CD25, NF-kB p50 and microRNAs
- Alimonti A. (2012) Manipulation of senescence pathways for cancer therapy: from experimental models to clinic
- Varani L. (2012) Antibodies against Dengue Virus: which ones are effective against this neglected disease and why? Searching for correlations between structural, dynamics and immunological properties of antibodyantigen complexes
- Sallusto F., Uguccioni M. (2012) Cell migration in tumorigenesis and metastasis
- Uguccioni M. (2012) TIMER - TargetIng novel MEchanisms of Resolution in inflammation
- Lanzavecchia A., Sallusto F., Uguccioni M. (2011) ADITEC - Advanced Immunization Technologies
- Sallusto F. (2011) IDAMS - International Research Consortium on Dengue Risk Assessment, Management and Surveillance
- Sallusto F. (2011) Cell Migration
- Alimonti A. (2011) PICS THERAPY - Manipulation of senescence pathways for cancer therapy: from experimental models to clinic
- Varani L. (2011) RADAR - Rationally Designed Aquatic Receptors integrated in label-free biosensor platforms for remote surveillance of toxins and polluants
- Zucca E. (2011) IELSG32 - Randomised phase II trial on initial therapy with high-dose methotrexdate and high-dose cytarabine with or without thiotepa and/or rituximab, followed by brain irradiation vs. autologous stem cells transplantation for primary CNS lymphoma
- Lanzavecchia A., Catapano C., Thelen M., Uguccioni M., Varani L. (2010) Analysis of the human immune response using high-throughput cellular screening
- Lanzavecchia A. (2010) IMMUNExplore - New approaches to analyze and exploit the human B and T cell response against viruses
- Sallusto F. (2010) Effector and memory T cell subsets in man and mouse
- Grassi F. (2010) i-IronIC - Implantable/Wearable System for on-line Monitoring of Human Metabolic Conditions
- Sallusto F. (2010) NEWTBVAC - Discovery and preclinical development of new generation tuberculosis vaccines
- Grassi F. (2010) Innovative enabling micro-nano-bio-technologies for implantable systems in molecular medicine and personalized therapy
- Catapano C. (2010) DENANORNA - Dendrimers as nanovectors for targeted siRNA delivery in gene therapy
- Catapano C. (2009) Small RNA-based transcriptional control of cancer genes
- Uguccioni M. (2009) MD - THIV - Migration and differentiation of Th17 cells in HIV/SIV infection
- Lanzavecchia A. (2009) The role of innate receptors in dendritic cell and B lymphocyte activation
- Molinari M. (2009) NCCR Neuro (sub-project Neural Plasticity and Repair)
- Grassi F. (2009) Purinergic signaling in T cell physiology
- Varani L. (2009) Prediction and characterization of antibody-protein interactions in Dengue virus
- Monticelli S. (2009) Role of microRNAs in the development and function of cells of the immune system
- Molinari M. (2009) Protein folding, quality control and degradation in the endoplasmic reticulum: Assessing the function of ER-resident molecular chaperones and folding factors
- Kwee I., Bertoni F. (2008) A Bayesian Approach for Integrated Cancer Genome Profiling 2
- Lanzavecchia A. (2008) IMECS - Identification of mechanisms correlating with susceptibility for avian influenza
- Lanzavecchia A., Sallusto F. (2008) PEMPHIGUS - From autoimmunity to disease
- Uguccioni M. (2008) Impact of Multiple Chemokine Expression in Human Disease
- Carbone G., Bertoni F., Catapano C. (2007) The epithelial specific ETS transcription factor-3 as a tumor suppressor in prostate cancer
- Thelen M., Grassi F., Molinari M., Uguccioni M. (2007) Fast laser scanning confocal microscope for real-time investigation of subcellular immunological and cell biological processes
- Kwee I., Bertoni F. (2007) A Bayesian Approach for Integrated Cancer Genome Profiling
- (2007) Regulation of dendritic cell development from hematopoietic stem and progenitor cells
- Sallusto F. (2007) Memory T cell subsets in man and mouse: identification, characterization and function
- Grassi F. (2007) Signaling microdomains in T cell development
- Lanzavecchia A. (2007) HUMALMAB - Human monoclonal antibodies as tools in malaria reserach and therapy
- Catapano C. (2006) Gene selective transcriptional repression by antigene oligonucleotides
- (2006) TRIM5 and Innate Resistance to HIV-1
- Grassi F., Sallusto F. (2006) Calcium Signalling in the regulation of the T cell response/calcium imaging unit
- Thelen M. (2006) Chemokine receptors and signal transduction pathways in leukocytes
- Lanzavecchia A. (2006) The role of innate receptors in dendritic cell and B lymphocyte activation
- Lanzavecchia A., Sallusto F. (2006) INTEGRAMM - International graduate programme in molecular medicine
- (2006) Regulation of adaptive immune responses by NK cells
- Molinari M. (2006) Protein folding, quality control and degradation in the endoplasmic reticulum: Assessing the function of ER-resident molecular chaperones and folding factors
- Uguccioni M. (2006) DEC-VAC - Development of a Dendritic Cell-targeted Vaccine against AIDS
- Sallusto F., Thelen M., Uguccioni M. (2005) INNOCHEM - Innovative Chemokine-based Therapeutic Strategies for Autoimmunity and Chronic Inflammation
- Sallusto F. (2005) SENS-IT-IV - Novel testing strategies for in vitro assessment of allergens
- Lanzavecchia A., Sallusto F., Uguccioni M. (2005) DC-THERA - Dendritic cells for novel immuotherapies
- Lanzavecchia A., Grassi F., Sallusto F. (2005) MUGEN - Integrated functional Genomics in mutant mouse models as tools to investigate the complexity of Human Immunological Disease
- Uguccioni M. (2005) TIP-VAC - Explaining and Improving Efficacy of targeted Immunodeficiency Virus-like Particles against AIDS
- (2004) Characterization of the molecular targets of the human T cell response to an alternative open reading frame (alt ORF) of the Hepatitis C Virus
- Grassi F. (2004) Molecular requirements and subcellular routing of signals in pre-T cell development and leukemogenesis
- Lanzavecchia A. (2004) SARSVAC - Immunoprevention and immunotherapy of SARS infection
- Pagani Santoro O. (2004) Translating molecular knowledge into early breast cancer management: building on the BIG (Breast International Group) network for improved treatment tailoring - TRANS-BIG
- Lanzavecchia A., Sallusto F., Thelen M., Uguccioni M. (2004) MAIN - Targeting cell migration in chronic inflammation
- Sallusto F. (2004) TB-VAC - An Integrated Project for New Vaccines against Tuberculosis
- Lanzavecchia A. (2003) MUVAPRED - Mucosal Vaccines for Poverty Related Diseases
- (2003) Development and characterization of a mouse model to study the human hematopoietic and immune system in vivo
- Sallusto F. (2003) Dissection of human memory T lymphocytes
- Thelen M. (2003) Chemokine receptor activated signal transduction pathways
- Thelen M. (2003) Chemokine receptor activated signal transduction pathways.
- Uguccioni M. (2002) MUVADEN - Mucosal Vaccines Against Human and Simian Immunodeficiency Viruses Based on Dendritic Cells
- Molinari M. (2002) Protein folding and quality control in the endoplasmatic reticulum. Assessing the function of ER-resident molecular cheperones and folding factors
- (2002) Mechanisms regulating activation and termination of Nuclear Factor kappa B (NF-kB) - dependent transcriptional responses
- Sallusto F. (2001) MEMOVAX - Immunological memory and vaccination
- Thelen M. (2001) Chemokine receptor mediated signal transduction in HIV infection
- Lanzavecchia A. (2001) Dendritic cells: origin, maturation and impact on T cell responses
- (2000) Human in vitro studies using Hepatitis C virus expression systems to study mechanisms of viral persistence and develop immunization strategies
- Thelen M. (2000) Molecular mechanisms of signal transduction
- (2000) B1 - immune correlates of protection and chronicity in hepatitis c virus infection
- (2000) C1 - Vaccine delivery systems for the development of preventive and therapeutic interventions against hepatitis C
- Uguccioni M. (2000) DETEC - SIV/HIV vaccines - detecting efficacy and explaining inefficacy
- (1999) Characterization of a novel pathway of multidrug resistance highly conserved from fission yeast to human
