Facoltà di scienze biomediche
Progetti
In corso (25)
- Sallusto F. (2020) New approaches to study T cell activation, differentiation and plasticity in humans
- González F. S., Krause R. (2019) IMMUNEMAP – Enabling data-driven immunological research by making two-photon intravital microscopy data FAIR
- Theurillat J. (2019) Deciphering and Targeting the Cancer Ubiquitylome
- Molinari M. (2019) Protein folding, quality control and degradation in the endoplasmic reticulum III
- Varani L. (2019) Characterization of antibody-antigen interactions in human pathogens II
- Guarda G. (2019) Deciphering the divergent roles of phosphatases in PD-1 and cytokine signalling
- Geiger R. (2019) The development of a platform to rapidly identify tumor antigen-specific T cells receptors for therapy
- Geiger R. (2019) TIL-FIT - Increasing the fitness of tumor-infiltrating T cells for cellular immunotherapy
- Sallusto F. (2019) Lymphocyte T helper (Th) cell differentiation in patients with inborn errors of immunity to Mycobacterium and/or Candida species
- Thelen M. (2018) Function of ACKR3 in immune cell trafficking in lymphoid organs
- Alimonti A. (2018) Development of senolytic therapies for chemotherapy-treated prostate cancer
- Theurillat J. (2018) Understanding Synthetic Sick Interactions of Prostate Cancer Driver Genes
- Monticelli S. (2018) Transcriptional control of human T lymphocyte pathogenic potential in autoimmunity
- González F. S. (2017) Role of lymph node phagocytes in the regulation of the IgG-mediated suppression of the immune response to influenza vaccine
- Lanzavecchia A. (2017) Antibody diversification by templated insertions: impact, mechanism and exploitation
- Cejka P. (2017) Beyond DNA end resection: Role of homologous recombination in the maintenance of genome stability
- González F. S. (2017) TANTUMorNEUVACCINE - Neutrophil subtypes: distinct cellular targets for therapeutic intervention
- Sallusto F. (2017) Rheuma Tolerance for Cure (RTCure)
- Monticelli S. (2017) NCCR RNA & Disease
- Catapano C., Zerbini Luiz, Carbone G. (2017) Epigenetic cross-talks and novel therapeutic strategies to prevent disease progression in ERG fusion positive prostate cancer
- Cejka P. (2016) HRMECH - Nucleases in homologous recombination: from basic principles to genome editing
- Limongelli V. (2016) Extensive computer simulations investigate TPP1-TERT protein-protein interaction
- Alimonti A. (2016) Immune-senescence – Dual targeting of senescence and tumor immunity for cancer therapy
- Lanzavecchia A. (2016) EHVA - European HIV Vaccine Alliance: an EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates
- Lanzavecchia A. (2015) BROADimmune - Structural, genetic and functional analyses of broadly neutralizing antibodies against human pathogens
Conclusi (89)
- Albanese E. (2018) Impatto della malattia di Alzheimer e di altre forme di deterioramento cognitivo in Ticino
- Theurillat J. (2017) Genetically-Induced Aberrant Chromatin States in Prostate Cancer - Biology and Therapy
- Catapano C., Wünsch Bernhard (2017) Targeting metabolic reprogramming and plasticity of cancer stem cells to impact on tumor progression and treatment resistance
- Rossi D., Bertoni F., Stüssi Georg (2017) Molecular prediction of long term benefit from ibrutinib in high risk chronic lymphocytic leukemia
- Grassi F. (2017) Role of ATP gated ionotropic P2X7 receptor in regulating adaptive mucosal immunity, host-microbiota mutualism
- Sallusto F. (2016) Studies on T cell activation, differentiation and plasticity in humans
- Sallusto F. (2016) ZIKAlliance - A global alliance for Zika virus control and prevention
- Cavalli A. (2016) Identification of structural determinants of light chain amyloidosis
- Guarda G. (2016) T Cell-Intrinsic Role of Pattern Recognition Receptors
- Varani L. (2016) Characterization of antibody-antigen interactions in human pathogens
- Bertoni F., Zucca Emanuele (2016) Targeted agents in splenic marginal zone lymphoma: mechanisms of resistance and new combinations
- Molinari M. (2016) Protein folding, quality control and degradation in the endoplasmic reticulum II
- Thelen M. (2015) Interplay of classical and atypical chemokine receptors in immune cell trafficking and dynamic microarchitecture of the secondary lymphoid organs
- Manconi M., Cajochen Christian (2015) Perinatal depression: chronobiology, sleep related risk factor and light therapy
- Thelen M. (2015) The Atypical Chemokine Receptor ACKR3: Function in vivo in Immune Responses and Coupling to Signal Transduction Pathways
- Varani L., Catapano C., Cavalli A., Lanzavecchia A., Thelen M., Uguccioni M. (2015) Acquisition of a 600 MHz solution NMR spectrometer
- Cejka P. (2015) Repair of damaged DNA by homologous recombination and related pathways
- Lanzavecchia A. (2015) Analytic vaccinology
- Grassi F. (2015) Systemic impact of purinergic P2X7 receptor activity at the interface between gut-associated lymphoid tissue and commensal microflora
- Monticelli S. (2015) DNA methylation landscape in mast cell differentiation and systemic mastocytosis
- Molinari M. (2014) ER-phagy mechanisms to maintain and restore endoplasmic reticulum homeostasis
- Engelhardt Britta, Sallusto F. (2014) Unraveling the immune etiology of multiple sclerosis – UnmetMS
- González F. S. (2014) A massively parallel space-time connected approach based on implicit active contour methods to track leukocytes observed by multiphoton intra vital and confocal microscopy
- González F. S. (2014) IMPORED - Intravital imaging of polymicrobial respiratory diseases
- Varani L. (2013) Mass Virus Typer: New Technology for Direct Virus Characterization
- Carrara Sandro, Grassi F. (2013) Innovative Enabling Micro-Nano-Bio-technologies for Implantable systems in molecular medicine and personalized therapy - Project prolongation
- González F. S. (2013) IRINVAC - Immune responses to influenza vaccine
- Lanzavecchia A. (2013) Tuning of immune homeostasis and immune response by persistent viral infections
- Sallusto F. (2013) PREDICT - Dissecting the human T cell response to pathogens, allergens, and self-antigens
- Uguccioni M. (2013) Impact of Synergy-inducing Molecules on Chemokine Activities
- González F. S. (2012) Immunity to flu vaccine
- Bourquin Carole, Sallusto F., Uguccioni M. (2012) ProDoc Cell Migration Research Module 3: Soluble factors in Cell Migration
- Grassi F. (2012) TIROTAPS - Transient Receptor Potential Melastatin-like 7 (TRPM7) in Regulation of T cell subsets and Purinergic Signaling
- Thelen M. (2012) Conventional and atypical chemokine receptors: different mechanisms of function and common responses
- Lanzavecchia A. (2012) Human B cells and plasma cells in health and diseases
- Varani L. (2012) Antibody-antigen interactions in Dengue virus
- Lanzavecchia A. (2012) LINFOEPAB - CD4 T and B lymphocytes in hepatitis B patients: role in acute and chronic infection
- Molinari M. (2012) Protein folding, quality control and degradation in the endoplasmic reticulum
- Grassi F. (2012) Purinergic control of adaptive immunity by P2X7 receptor
- Lanzavecchia A. (2012) ABIRISK - Anti-Biopharmaceutical Immunization: Prediction and Analysis of Clinical Relevance to Minimize the Risk
- Monticelli S. (2012) Analysis of novel molecular networks underlying mast cell development, function and disease: specific roles of CD25, NF-kB p50 and microRNAs
- Sallusto F. (2012) ProDoc Cell migration in tumorigenesis and metastasis
- Varani L. (2012) Antibodies against Dengue Virus: which ones are effective against this neglected disease and why? Searching for correlations between structural, dynamics and immunological properties of antibody-antigen complexes
- Uguccioni M. (2012) TIMER - TargetIng novel MEchanisms of Resolution in inflammation
- Lanzavecchia A., Sallusto F., Uguccioni M. (2011) ADITEC - Advanced Immunization Technologies
- Sallusto F. (2011) IDAMS - International Research Consortium on Dengue Risk Assessment, Management, and Surveillance
- Varani L. (2011) RADAR - Rationally Designed Aquatic Receptors integrated in label-free biosensor platforms for remote surveillance of toxins and pollutants
- Lanzavecchia A., Catapano C., Thelen M., Uguccioni M., Varani L. (2010) Analysis of the human immune response using high-throughput cellular screening
- Lanzavecchia A. (2010) IMMUNExplore - New approaches to analyze and exploit the human B and T cell response against viruses
- Sallusto F. (2010) Effector and memory T cell subsets in man and mouse
- Grassi F. (2010) i-IronIC - Implantable/Wearable System for on-line Monitoring of Human Metabolic Conditions
- Sallusto F. (2010) NEWTBVAC - Discovery and preclinical development of new generation tuberculosis vaccines
- Carrara Sandro, Grassi F. (2010) Innovative Enabling Micro-Nano-Bio-technologies for Implantable systems in molecular medicine and personalized therapy
- Lanzavecchia A. (2009) The role of innate receptors in dendritic cell and B lymphocyte activation II
- Uguccioni M. (2009) MD-THIV - Migration and Differentiation of Th17 Cells in HIV/SIV Infection
- Grassi F. (2009) Purinergic signaling in T cell physiology
- Monticelli S. (2009) Role of microRNAs in the development and function of cells of the immune system
- Molinari M. (2009) Protein folding, quality control and degradation in the endoplasmic reticulum: Assessing the function of ER-resident molecular chaperones and folding factors II
- Lanzavecchia A., Sallusto F. (2008) PEMPHIGUS - From autoimmunity to disease
- Lanzavecchia A. (2008) IMECS - Identification of mechanisms correlating with susceptibility for avian influenza
- Uguccioni M. (2008) Impact of multiple chemokine expression in human disease
- Sallusto F. (2007) Memory T cell subsets in man and mouse: identification, characterization and function
- Thelen M., Grassi F., Molinari M., Uguccioni M. (2007) Fast laser scanning confocal microscope for real-time investigation of subcellular immunological and cell biological processes
- Grassi F. (2007) Signaling microdomains in T cell development
- Lanzavecchia A. (2007) HUMALMAB - Human monoclonal antibodies as tools for malaria research and therapy
- Grassi F., Sallusto F. (2006) Calcium signalling in the regulation of the T cell response/calcium imaging unit
- Thelen M. (2006) Chemokine receptors and signal transduction pathways in leukocytes
- Lanzavecchia A. (2006) The role of innate receptors in dendritic cell and B lymphocyte activation I
- Lanzavecchia A., Sallusto F. (2006) INTEGRAMM - International graduate program in molecular medicine
- Molinari M. (2006) Protein folding, quality control and degradation in the endoplasmic reticulum: Assessing the function of ER-resident molecular chaperones and folding factors
- Uguccioni M. (2006) DEC-VAC - Development of a Dendritic Cell-targeted Vaccine against AIDS
- Uguccioni M. (2005) INNOCHEM - Innovative Chemokine-based Therapeutic Strategies for Autoimmunity and Chronic Inflammation
- Sallusto F. (2005) SENS-IT-IV - Novel testing strategies for in vitro assessment of allergens
- Lanzavecchia A., Sallusto F., Uguccioni M. (2005) DC-THERA - Dendritic cells for novel immunotherapies
- Uguccioni M. (2005) TIP-VAC - Explaining and Improving Efficacy of targeted Immunodeficiency Virus-like Particles against AIDS
- Lanzavecchia A., Grassi F., Sallusto F. (2005) MUGEN - Integrated functional genomics in mutant mouse models as tools to investigate the complexity of human immunological disease
- Uguccioni M. (2004) Impact of Multiple Chemokine Expression in Human Disease
- Lanzavecchia A. (2004) SARSVAC - Immunoprevention and immunotherapy of SARS infection
- Sallusto F. (2004) TB-VAC - An Integrated project for the design and testing of vaccine candidates against tuberculosis: Identification, development and clinical studies
- Uguccioni M., Lanzavecchia A., Sallusto F., Thelen M. (2004) MAIN - Targeting cell migration in chronic inflammation
- Lanzavecchia A. (2003) MUVAPRED - Mucosal Vaccines for Poverty Related Diseases
- Sallusto F. (2003) Dissection of human memory T lymphocytes
- Thelen M. (2003) Chemokine receptor activated signal transduction pathways
- Uguccioni M. (2002) MUVADEN - Mucosal vaccines against human and simian immunodeficiency viruses based on dendritic cells
- Molinari M. (2002) Protein folding and quality control in the endoplasmatic reticulum. Assessing the function of ER-resident molecular chaperones and folding factors
- Sallusto F. (2001) MEMOVAX - Immunological memory and vaccination
- Lanzavecchia A. (2001) Dendritic cells: origin, maturation and impact on T cell responses
- Thelen M. (2001) Chemokine receptor mediated signal transduction
- Uguccioni M. (2000) DETEC - Siv/hiv vaccines: detecting efficacy and explaining inefficacy
